Search Tag: Alzheimer’s disease

2020 30 Nov

Anxiety is associated with an increased rate of progression from mild cognitive impairment to Alzheimer's disease, according to a study being presented at the annual meeting of the Radiological Society of North America (RSNA). Alzheimer's disease represents a major public health crisis worldwide. The number of deaths from the disease has more than...Read more

2020 17 Jul

Scientists, researchers and clinicians have spent decades trying to find a cure for Alzheimer's disease (AD). In a session at #ECR2020 Digital Congress, imaging experts talked about Alzheimer's disease and neurodegeneration: visualising the invisible.   Lydiane Hirschler and Meike Venooij of the Netherlands and Javier Arbizu of Spain showed how...Read more

2019 03 Dec

The blood-brain barrier (BBB) is a network of blood vessels and tissues that protects the brain from foreign substances. BBB poses a challenge to scientists working on new treatments because it also blocks potentially therapeutic drugs from reaching targets inside the brain.     You might also like: PET Imaging Tool Measures Synaptic...Read more

2019 19 Nov

Alzheimer’s disease (AD) is difficult to detect primarily because of the lack of measurable indicators – or biomarkers – before patients exhibit symptoms of this form of dementia. However, damage to the brain occurs years before AD is already symptomatic and advanced. New research from the University of Minnesota has looked into a promising...Read more

2018 18 Jul

Researchers in Spain have developed a new contrast agent for magnetic resonance imaging (MRI) based on functionalised magnetic nanoparticles that could work as a biomarker for early diagnosis of Alzheimer’s disease. Their work could pave the way for new studies that develop methods of early and noninvasive diagnosis of this neurodegenerative disease. ...Read more

2015 18 Sep

A new technique for creating transparent tissue has enabled Japanese researchers to visualise brain anatomy in 3D, giving them new insights into Alzheimer's disease plaques. "While Superman's x-ray vision is only the stuff of comics, our method, called Sca/eS, is a real and practical way to see through brain and body tissue," says lead scientist Atsushi...Read more

2015 28 Jul

An imaging study shows that specific cardiovascular risk factors, such as alcohol use, smoking, obesity and diabetes, correlate with smaller regional brain volumes that may be early indicators of Alzheimer’s disease and dementia. The findings are reported in the journal Radiology . Previous studies have linked cardiovascular risk factors and cognitive...Read more

2015 28 Jul

An imaging study finds a strong association between insulin resistance and lower brain glucose metabolism in a group of late middle-age adults at risk for Alzheimer's disease (AD). The findings are published online in JAMA Neurology. Insulin resistance, broadly defined as reduced tissue responsiveness to the action of insulin, is common in people who...Read more

2015 16 Jun

Using a powerful 9.4-Tesla MRI — the first of its kind for human imaging — researchers at the University of Illinois at Chicago have obtained the most detailed MRI images of the brain so far to show that while the brain shrinks with age, brain cell density remains constant. The findings are reported in the journal NMR in Biomedicine . The 9.4-Tesla...Read more

2015 08 Jun

A report published in American Journal of Neuroradiology (AJNR) discusses how cognitive decline can be identified early and prevented by applying quantitative brain imaging techniques. Amidst growing evidence that neurodegenerative diseases alter brain structures, use of quantitative brain imaging is gaining popularity among clinicians as this helps...Read more

2015 27 May

A new study published in Radiology reveals that degeneration of the brain's white matter may be an early marker of specific types of Alzheimer’s disease (AD), including early-onset AD. Researchers used diffusion tensor imaging (DTI) to assess the white matter tracts in 53 patients with three types of AD: early-onset AD and two atypical types of AD...Read more

2014 01 Dec

Based on findings of a new study, changes in brain connections visible on MRI could represent an imaging biomarker of Alzheimer's disease, the most common form of dementia. For this study, researchers examined the brain's structural connectome, a map of white matter tracts that carry signals between different areas of the brain. "The structural connectome...Read more