Search Tag: β-lactam serum concentrations

ICU Management

Study highlights complexity of drug pharmacokinetics in septic patients

2018 17 Jul

Augmented renal clearance (ARC) is commonly observed in septic patients and may result in insufficient β-lactam serum concentrations. In a new study, researchers evaluated potential correlations between drug concentrations or total body clearance of β-lactam antibiotics and measured creatinine clearance. They found that specific pharmacokinetic... Read more