In the year 1983 BIOREF GmbH was founded in Homburg / Saar (Germany). Since that time BIOREF organizes proficiency studies especially for tumor markers.
1985 BIOREF moved to the present company location (Moembris, Germany) - 50 km east from Frankfurt International Airport. Two years later BIOREF launched the first tumor marker reference material. The Multi-Analyte Tumor Marker Control Serum RM 16 has been improved continuously and is now a liquid and very stable control on physiological human serum matrix.
Since 1997 BIOREF also produces control sera for hormones and drugs (HD 50). The product range was expanded several times - now also control sera for cardiac markers (IM 5), thyroid hormones (TH 6) and plasma proteins (PP 15) can be offered.
The newest products are POCT Cardiac Marker Control Serum PC 10, Multi-Analyte Allergy Control Serum AL 20 and CSF (Cerebrospinal Fluid) Control LQ 10.
BIOREF has established a quality management system since many years which is certified according to ISO 9001 and ISO 13485. This quality management system is continuously adjusted to business as well as official requirements and it is regularly improved for the benefit of our customers.
The external surveillance of the quality management system is performed by MDC Medical Device Certification GmbH (Stuttgart, Germany), which is specialized on the certification of quality systems in medical device industry.