Laboratory applications for LC systems are very diverse, extending from the product development phase to verification of quality. Therefore, a modular all-round LC system that can be combined flexibly with other instruments to respond to all types of analyzers' needs is an essential laboratory tool. Nexera is an all-round LC system like no other and is truly worthy of being called a next-generation UHPLC system. It uses revolutionary technology to offer high-performance ultra-high speed LC analysis and the flexibility to allow configuring systems for a wide range of applications, such as systems for general-purpose analysis or green LC systems that reduce the usage of organic solvents.