The goal of high-speed HPLC from Shimadzu is to enhance the laboratorys productivity. We believe that analytical data obtained from high-speed HPLC must be as reliable as the data from conventional HPLC. For example, resolution must be maintained at an excellent level in the case of 10,000 analytical runs by high-speed LC, retention time and area repeatability must be excellent for small volume sample injection, the need for replacement parts should be minimized, and the instrument must work stably.We successfully achieved speed and separation performance levels that do not depend on high pressure, while simultaneously offering a high level of precision and expandability not available with previous fast LC systems. Thus, we see that UFLC realizes both high speed and analytical precision/reliability to achieve true analytical productivity enhancement.