The BagPRESS Bio45P is a blood component extractor that provides the automatically-controlled separation of erythrocytes (RCC), buffy-coat (BC), platelet poor plasma (PPP) or platelet rich plasma (PRP) and platelet concentrates. BagPRESS Bio45P is intended to make blood centres free to choose their own blood collection strategy either with standard pack configuration or with top and bottom pack configuration. As the separation process is automatic, a single person can operate several machines, simultaneously. The automation process also means that the blood components obtained are high quality and standardized. It could be built for sealing blood bag tubes. A powerful RF-unit makes it suitable for automatic routine procedures and repeated manual operations and the operator can easily pull the tube apart.