Special Supplement

Results from the French registry: GIHP-NACO Presents results from a registry detailing information about the management of bleeding patients in the emergency room, operating room or intensive care unit during therapy with direct oral anticoagulants. Background There is a large literature on the efficacy of direct oral anticoagulants (DOAC) to prevent stroke or systemic embolic events in patients wi

Presents the results from a randomised controlled trial which aimed to determine if fibrinogen concentrate infusion reduces intraoperative blood loss in cardiac surgery patients. Background Excessive bleeding is a common complication in cardiac surgery, and may result in the need for red blood cell (RBC) transfusion. Intraoperative bleeding during cardiac surgery is often treated with coagulation fa

RETIC study Presents results of the RETIC study that compared treatment of trauma-induced coagulopathy using coagulation factor concentrates or fresh frozen plasma. Background Trauma-induced coagulopathy (TIC) represents a clinical picture resulting from severity of injury, hypoperfusion, blood loss, consumption, dilution and platelet dysfunction. Activation of the protein C system seems to mediat

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