9th International Conference on Structural Biology
Start:
Mon, 18 Sep 2017, 08:00
End:
Tue, 19 Sep 2017, 05:00
Venue:
Exhibit
Symposia
Workshops
Organiser
Sponsor
Structural Biology 2017 mainly emphasizes on methods such as X-ray diffraction, NMR, electron microscopy, computational approaches, cell signalling and cancer research. Also it offers an ideal balance of scientific sessions and networking opportunities.
Important Dates
Abstract submission opens:
September 06, 2016
Registration opens: September 06, 2016
Early bird registration: December 31, 2016
On spot registration: September 18, 2017
Accommodation
A large number of rooms have
been reserved. Discounted room rates for Structural Biology 2017 participants
are proposed.
Only reservations made through the Conference will benefit these rates. The Congress Center can be easily reached by public transportation.
Exhibition and Sponsorship
An Exhibition will be held
concurrently with the Congress. The coffee break and lunch areas will be
located adjacent to the booths. Thanks to exhibitors
from all over the world, attendees will have a complete overview of new
findings in the fields of Structural Biology and Biophysics.
Highlights of the conference:
· 3D Structure Determination
· Computational Approaches in Structural Biology
· Hybrid Approaches for Structure Prediction
· Sequencing
· Structural Biology Databases
· Cell Signalling
· Molecular Modelling and Simulation
· Drug Designing
· Structural Biology in Cancer Research
· Frontiers in Structural Biology
· Structural Biology Complexity Arenas
· Recent Advances in Structural Biology
To Submit the Abstract Click Here
Track-1 3D Structure Determination
Biomolecules are very small
to see in detail even by most cutting-edge light microscopes. The methods that
the structural biologists use to determine their structures in general involve
the measurements on huge numbers of identical molecules at the same time. Some
of the best methods include X-ray crystallography, Cryo-Electron Microscopy and
Nuclear Magnetic Resonance. Very often scientists use them to study the
"native states" of biomolecules.
Track-2 Computational Approaches in Structural Biology
Computational approaches are
a boon for structural biology. In general the structure of molecules is
determined by experimental methods is both time intense and cost effective. To
overcome these constraints, computational approaches like ab-initio modelling,
homology modeling and threading method are used.
Track-3 Hybrid Approaches for Structure Prediction
Structural bioinformatics is
an exceptionally cost effective solution for protein structure determination.
Purely computational prediction methods, like ab initio fragment assembly,
advanced fold recognition, composite approaches, and molecular docking are
regularly applied today to extend our understanding of protein structures.
However, predicted structures are not given the same reliance as their
experimental complements. Hybrid approaches are a means to overcome these
limitations; by incorporating limited experimental measurements, reliable
structures can be computed and unlikely predictions eliminated. Hybrid
approaches take advantage of data derived from a wide range of different
biophysical and biochemical methods. These methods are of growing interest in
current researches of structural biology.
Track-4 Deep Sequencing
Deep Sequencing meets structural
biology is a dedicated track to show how the recently developed methods are
used to determine the structure of molecules. This approach proves itself
helpful in a more efficient way. Synergistic use of three-dimensional
structures and deep sequencing is done to realize the effect of personalized
medicine.
Track-5 Structural Biology Databases
A database is a structured
collection of data. In the field of structural biology enormous research is
being done and as a result massive data is being produced. In order to pile the
data in an organized manner, bioinformatics databases are used. Various databases
have been created to store biological data, such as sequence databases,
structure databases, signalling pathway databases, etc. In the field of
structural biology, the mainly used databases are Protein Data Bank (PDB),
Electron Microscopy Data Bank, Protein Structure Classification Database (CATH)
and Structural Classification of Protein (SCOP).
Track-6 Signalling Biology
Regulation of gene
expression comprises a comprehensive range of mechanisms that are used by cells
to regulate the production of specific gene products, and is familiarly termed
as gene regulation. Sophisticated programs of gene expression are extensively
observed in biology, for example to trigger developmental pathways, adapt to
new food sources, or respond to environmental stimuli. Essentially any step of
gene expression can be modulated, from transcription initiation to post
translation modification of a protein.
Track-7 Molecular Modelling and Simulation
Molecular modelling and
simulation embraces all the hypothetical methods and computational procedures
used to mimic the behaviour of macromolecules. These techniques are used in
diverse fields of drug design, computational chemistry, materials science and
computational biology for studying macromolecular systems ranging from small to
large biological systems. Simplest calculations can be achieved by hand, but
certainly computers are essential to perform molecular modelling of reasonably
sized system. Molecular simulation on the other hand uses powerful computers to
simulate the interactions between atoms and to understand the properties of
materials. Such simulations involve methods that range from very detailed
quantum mechanical calculations on atoms to coarse-grained classical dynamics
of large groups of molecules on a timescale of milliseconds or longer.
Track-8 Drug Designing
Drug design is also referred
as rational drug design. It is an inventive process to find new medication
centred on the knowledge of biological target. Drug is most commonly a small
molecule that inhibits or activates the function of a biomolecule, which in
turn outcomes in a therapeutic benefit to the patient. Drug design commonly but
not essentially relies on computational techniques. This type of modelling is
often mentioned to as computer-aided drug design. Drug design that depends on
the knowledge of the 3D structure of the target is known as structure-based
drug design. The main methods available for drug design are structure based
drug design and ligand based drug design.
Track-9 Frontiers in Structural Biology
The main focus of a
structural biologist is protein structure determination and drug design.
Protein plays an important role in human body. Living things would not exist
without proteins. Proteins are involved in all aspects of living things.
Several proteins provide structure to cells; others tend bind to and carry
vital molecules all through the body. Some proteins are involved in biochemical
reactions in the body which are termed as enzymes. Others are involved in
muscle contractions and immunity. Structure determination of proteins has
always been a challenging filed. The complex areas in the field include
viruses, pathogens, membrane proteins and signalling pathways. Novel
progressions are being done in the arenas of nanopatternig and multi scale
modelling of cell signalling proteins.
Track-10 Structural Biology in Cancer Research
Major part of research is
being carried out in the area of cancer. The main aim is to design and discover
novel and effective drugs to cure the disease. Structural biology combined with
molecular modelling mainly aims at drug designing. Subsequently, numerous team
leaders in Structural biology carry out cancer research to accelerate the
exploitation of molecular understanding of biomolecules in the advancement of
novel cancer therapies.
Track-11 Structural Biology Complexity Arenas
Structural biology aims at
understanding biomolecules at atomic level. All most all aspects in structural
biology research seem to be complex. Researchers have been proven to be
successful in solving many of the complexities like determination of protein
structures, functional annotations and drug designing. Though structures of
proteins are solved on a huge scale, the gap between available sequence data
and structure data is enormous. Bridging this gap is one of the main
challenges. In the current research, some of the most complex areas are protein
folding, catching the complication of dynamic nanomachines and signalling
networks, understanding the intrinsically disordered proteins.
Track-12 Recent Advances in Structural Biology
Structural biology is one of
the expanding fields. In the course of time many advances have taken place.
Huge number of solved structures has amplified rapidly. The field of drug
design and drug discovery has been advanced. Functional annotations are another
field where progressions are being seen. Alterations in order to improve the
effectiveness of prevailing tools can also be noted. Remarkable advances can be
seen in the areas of imaging technologies and advancement of hybrid methods to
understand the structure and function of proteins.
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