Understanding of contemporary pharmacological therapy for chronic heart failure continues to evolve. In a recent review (Medical Therapy for Chronic Heart Failure, The Lancet, Volume 378, Issue 9792, Pages 713 - 721, 20 August 2011), Prof. Krum and colleagues discuss how findings from clinical trials have caused the roles of old therapies to be expanded and past treatment algorithms to be challenged. Several trials investigating preserved ejection fraction as a measure of heart failure had disappointing results, although important studies are in progress. Many novel therapeutic approaches for heart failure have emerged and are discussed in this review. The pharmacological treatments for heart failure continue to change, with many exciting possibilities for the future. The authors discuss how findings from clinical trials have caused the roles of old therapies to be expanded and past treatment algorithms to be challenged. Several trials investigating preserved ejection fraction as a measure of heart failure had disappointing results, although important studies are in progress. Many novel therapeutic approaches for heart failure have emerged and are discussed in this review. The pharmacological treatments for heart failure continue to change, with many exciting possibilities for the future.

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Understanding of contemporary pharmacological therapy for chronic heart failure continues to evolve. In a recent review (Medical Therapy for Chronic Heart...